Application Data\Microsoft\VisualStudio\8.0in your home directory. That sucks because you lose your window settings and some other layout stuff and it's a PITA to reload that every time. It's not quite so much a PITA if you save a copy of that folder off somewhere immediately after entering a new VS2005B2 session. You can then use a batch file to delete the corrupted profile folder and copy a fresh one back over, like so:
rmdir /s /q "C:\Documents and Settings\Jim Admin\Application Data\Microsoft\VisualStudio\8.0\" xcopy /s /e "C:\Documents and Settings\Jim Admin\My Documents\VS 8.0 Backup Settings" "C:\Documents and Settings\Jim Admin\Application Data\Microsoft\VisualStudio\8.0\"Note the trailing slash on the target folder -- saves a prompt asking if the target's a folder or file. This all goes pretty quickly, especially if you're using SlickRun for quickly launching such utils.